Despite their on-again, off-again relationship in the past, Leonard and Penny have finally gotten married. Even Sheldon has found a female companion, entering into a 'relationship agreement' with neurobiologist Amy Farrah Fowler, and he recently took their relationship to the next level by marrying her after a long courtship. Will their equation for marital bliss alter the chemistry between these two beautiful minds? Quantum comedy converges in the twelfth dimension!