Kate Bishop is in a world of trouble. In the wake of several inexplicable and brutal murders, Kate is thrust into a police inquiry that reveals shocking family secrets. Suddenly exposed to a shadowy network of global evil, her life takes a dramatic turn with the arrival of Jack Raines, an author with a mysterious past, who says he has the answers to her questions. What's more, he suggests that Kate herself might be the solution. But hot on their heels are a force of super-predators, vicious and bloodthirsty killers who will stop at nothing until Kate and Jack are eliminated. Like Jack, they've realized just how special Kate is, and now she's marked for death.